This was said by the Lord…

“Bhikkhus, I do not perceive any single hindrance other than the hindrance of ignorance by which humankind is so obstructed and for so long a time runs on and wanders in saṃsāra. It is indeed through the hindrance of ignorance that humankind is obstructed and for a long time runs on and wanders in saṃsāra.”

No other single thing exists
Like the hindrance of delusion,
Which so obstructs humankind
And makes it wander on forever.

Those who have abandoned delusion,
Cleaving through this mass of darkness,
No longer roam and wander on;
In them the cause is found no more.